Author(s) :

Shamanth Devraj.

Volume/Issue :

Abstract :

Point-of-care (POC) diagnostic devices have revolutionized healthcare by enabling rapid, accurate, and on-site detection of diseases, thereby facilitating timely clinical decisions and improved patient outcomes. The integration of nanotechnology into POC diagnostics has significantly enhanced device sensitivity, specificity, and multiplexing capabilities. Nanomaterials such as gold nanoparticles, quantum dots, carbon nanotubes, and magnetic nanoparticles provide unique optical, electrical, and magnetic properties that can be harnessed to develop miniaturized, portable, and highly efficient biosensors. This paper comprehensively reviews the advancements in nanotechnology-enabled POC devices, focusing on the design principles, nanomaterial applications, and the challenges faced in clinical translation. It highlights successful case studies including COVID-19 rapid tests, glucose sensors, and infectious disease diagnostics. Finally, it discusses future perspectives involving smart wearable diagnostics, integration with digital health platforms, and the role of artificial intelligence in enhancing POC testing.

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