ELECTROSPINNING AND FORMATION OF NANOFIBROUS WOUND HEALING MATERIAL BASED ON BIOPOLYMER
Krishnaja. P.V1, Akshay Krishnan U.S2, S. Karthik Sundaram.3
ABSTRACT In order to create the ideal microenvironment for effective tissue repair, wound dressings are crucial. An ideal dressing prevents microbial contamination of the wound, preserves moisture balance, permits gaseous exchange, absorbs excess exudate, and promotes extracellular matrix formation and cell proliferation. Appropriate dressing materials minimize pain, speed up healing, and prevent scarring in both acute and chronic wounds. However, there are a number of drawbacks to traditional wound dressings like cotton bandages and gauze. They frequently stick to the surface of the wound, inflict further damage when removed, retain moisture poorly, and provide little antimicrobial protection. difficulties in creating cutting-edge materials for wound dressings Key: One of the main challenges in creating materials for wound healing is striking the ideal balance between moisture retention and exudate absorption. The main obstacles may also include preventing microbial colonization without causing cytotoxicity, guaranteeing biocompatibility and non-immunogenicity, and offering adequate mechanical strength and flexibility. It’s also crucial to enable controlled drug or bioactive agent released. Keywords: Wound dressings, Tissue repair and regeneration, Moisture balance, Exudate absorption, antimicrobial protection, Biocompatibility, Controlled drug release.

